Three doses of 3 g fosfomycin tromethamine dosing regimen is efficacious and safe in acute uncomplicated cystitis, recurrent lower urinary tract infection and complicated lower urinary tract infection. BMJ Open. 2013 Dec 4:3(12):e004157.
Well tolerated and safe during pregnancy, offers quality-of-life advantages. Int J Fertil Womens Med. 1999 Mar-Apr:44(2):104-9.
Single 3-gram dose of fosfomycin is as effective as ciprofloxacin, at 500mg t.i.d for 5 days, in the treatment of acute uncomplicated cystitis. Journal of Infection and Chemotherapy Volume 16, Issue 6. 2010, Pages 424-430
Preferred first line oral formulation due to its higher bioavailability, (33% to 44%), compared to the calcium salt (12-37%) Chemotherapy, 1993:39:297-301, Infection. 1990:18:865-869, Antimicrob. Agents Chemother. 1981;20:393-397, Chemotherapy, 1977;23:159-174.
Single dose of 3 g administered every 72 h achieves appropriate urinary concentrations along 7 days, in lower UTI. Enferm Infecc Microbiol Clin: 2006 Nov:24(9):546-50.