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ZIDIGGEN 3 Gm/1.5 Gm Injection
Ceftazidime 2 gm + Sulbactam 1 gm
Ceftazidime 1 gm + Sulbactam 500 mg
When Alone Fails to Deliver
CEFTAZIDIME
Third-generation cephalosporin with broad-spectrum activity against gram-positive and gram-negative aerobic bacteria,
1
Clinically effective for treating respiratory tract infections such as hospital-acquired pneumonia.
2
Ceftazidime penetrates well into tissues, body fluid, and cerebrospinal fluid.
3
Efficacious in treatment of Urinary tract infections, skin infections, bone and joint infections as well as gynecologic infections.
SULBACTAM
Shows intrinsic activity against multidrug-resistant Acinetobacter baumannii.
4
Irreversibly inhibits the hydrolytic activity of beta-lactamases.
5
CEFTAZIDIME AND SULBACTАМ
A fixed-dose combination of ceftazidime plus sulbactam is more potent than ceftazidime alone.
6
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Combined to Combat
Dosage
1.5gm/3gm administered intravenously or intramuscularly every 8 to 12 hours
Combined to Combat
Drugs 1985 Feb, 29(2) 105-61
Expert Opin Pharmacother. 2012 Oct: 13(14):2097-109 Jan. 14 Suppl 1:1858
Pharmacotherapy Sep-Oct 1985; 5(5): 254-67
Braz J Microbiol 2015 Oct-Dec; 46(4): 119-1124
Clin Microbiol infect 2008
Flora Microbiol 54,391(2009)
Indication
Respiratory tract infections
Bone and joint infections
Urinary tract infections
Skin and soft tissue infections
Gynecologic infections
Meningitis
Cystic fibrosis
Pneumonia
Septicemia
Bactetaemia
Peritonitis
Acute otitis media